Article
Detection and molecular characterisation of a diagnosis escape variant associated with occult hepatitis B virus in Brazil.
Memorias do Instituto Oswaldo Cruz - 1 Jul 2017
Almeida Ricardo Wagner de, Mello Francisco Campello do Amaral, Menegoy Isabelle Vasconcelos, Santo Márcia Paschoal do Espírito, Ginuíno Cléber Ferreira, Sousa Paulo Sérgio Fonseca de, Villar Livia Melo, Lampe Elisabeth, Lewis-Ximenez Lia Laura
Abstract excerpt
BACKGROUND: Many studies have identified mutations in the hepatitis B surface antigen (HBsAg) as important factors limiting the ability of commercial serological assays to detect this viral antigen. However, an association between mutations in the HBsAg gene and the occurrence of occult HBV infection (OBI) in patients has not been established. OBJECTIVES: To detect hepatitis B virus (HBV) DNA in patients with...
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