Article
N termini of apPDE4 isoforms are responsible for targeting the isoforms to different cellular membranes.
Learning & memory (Cold Spring Harbor, N.Y.) - 1 Sept 2010
Jang Deok-Jin, Park Soo-Won, Lee Jin-A, Lee Changhoon, Chae Yeon-Su, Park Hyungju, Kim Min-Jeong, Choi Sun-Lim, Lee Nuribalhae, Kim Hyoung, Kaang Bong-Kiun
Abstract excerpt
Phosphodiesterases (PDEs) are known to play a key role in the compartmentalization of cAMP signaling; however, the molecular mechanisms underlying intracellular localization of different PDE isoforms are not understood. In this study, we have found that each of the supershort, short, and long for...
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