Article
Dual acylation of PDE2A splice variant 3: targeting to synaptic membranes.
The Journal of biological chemistry - 18 Sept 2009
Russwurm Corina, Zoidl Georg, Koesling Doris, Russwurm Michael
Abstract excerpt
The cGMP-stimulated PDE2A hydrolyzes both cyclic nucleotides, cGMP and cAMP. Three splice variants have been cloned from several species. Whereas PDE2A1 is soluble, PDE2A2 and PDE2A3 are membrane-bound enzymes of rat and bovine origin, respectively. To date it is unclear whether one species expre...
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