Article

The intracellular targeting and regulation of PDE4 cyclic AMP-specific phosphodiesterase enzymes

2000-01-01

Abstract excerpt

Cyclic adenosine 5': 3' monophosphate (cAMP) is a ubiquitous second messenger in cells which transduces the action of a wide variety of hormones and neurotransmitters. cAMP phosphodiesterase (PDE) enzymes provide the sole route for the degradation of cAMP and are thus placed in a key position for regulating cAMP-dependent processes. The cAMP-specific PDE4 enzyme family are encoded by four genes (PDE4A, -B, -C and...

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Literature Corpus work: d05c5839-8cf6-562e-885e-3f0d5e477b90
DOI: 10.5525/gla.thesis.71220

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