Article

Phosphodiesterase Type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins

2020-09-11

Abstract excerpt

Cyclic AMP is a ubiquitous second messenger used to transduce intracellular signals from a variety of Gs-coupled receptors. Compartmentalisation of protein intermediates within the cAMP signaling pathway underpins receptor-specific responses. The cAMP effector proteins protein-kinase A and EPAC are found in complexes that also contain phosphodiesterases whose presence ensures a coordinated cellular response to rec...

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Literature Corpus work: 341768de-9822-596c-bae5-616d400fc3a7
DOI: 10.1101/2020.09.10.290825

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