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Article

CRISPR-cas9-Mediated Gene Editing to Reverse Oncogenic Mutations in Oral Squamous Cell Carcinoma.

Annals of African medicine - 1 Jul 2026

Awinashe Minal, Viswaja K, Pathath Abdul Wahab, Subair Fahida P, Varshney Anchal, Mishra Pallavi, Mulla Mushir, Mulla Munaz

Abstract excerpt

INTRODUCTION: Oral squamous cell carcinoma (OSCC) is a genetically driven malignancy characterized by a high burden of oncogenic mutations that contribute to aggressive tumor behavior, therapeutic resistance, and poor survival outcomes. Conventional treatment modalities largely target downstream molecular pathways without correcting the underlying genetic aberrations, underscoring the need for precision-based...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41837831
DOI: 10.4103/aam.aam_864_25
PMCID: PMC13374948

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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