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Article

Mutations of the BRAF gene in squamous cell carcinoma of the head and neck.

Oncogene - 24 Jul 2003

Weber Anette, Langhanki Larissa, Sommerer Florian, Markwarth Annett, Wittekind Christian, Tannapfel Andrea

Abstract excerpt

The RAF/MEK/ERK (MAPK) signal transduction cascade is an important mediator of a number of cellular fates including growth, proliferation and survival. The BRAF gene, one of the human isoforms of RAF, is activated by oncogenic RAS, leading to cooperative effects in cells responding to growth factor signals. This study was performed to elucidate a possible function of BRAF in squamous cell carcinoma of the head...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12879021
DOI: 10.1038/sj.onc.1206705

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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