Article
Effects of KRAS mutation and polymorphism on the risk and prognosis of oral squamous cell carcinoma.
Head & neck - 1 May 2012
Wang Wen-Yi, Chien Yi-Chih, Wong Yong-Kie, Lin Yan-Liang, Lin Jin-Ching
Abstract excerpt
BACKGROUND: Mutations or single nucleotide polymorphism (SNP) of relevant genes may affect the risk and prognosis of malignancies. The purpose of this study was to analyze whether the KRAS polymorphisms and mutations can be useful prognostic or risk markers in oral squamous cell carcinoma (OSCC). METHODS: DNA was extracted from tumor tissues of 47 patients with OSCC and blood cells of 84 normal controls and...
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