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Article

PDCD2 is essential for inner cell mass development and embryonic stem cell maintenance.

Developmental biology - 15 Nov 2010

Mu Weipeng, Munroe Robert J, Barker Anna K, Schimenti John C

Abstract excerpt

PDCD2 is a conserved eukaryotic protein implicated in cell cycle regulation by virtue of its interactions with HCFC1 and the NCOR1/SIN3A corepressor complex. Pdcd2 transcripts are enriched in ES cells and other somatic stem cells, and its ortholog is essential for hematopoietic stem cell maintena...

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Source

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Identifiers

PMID: 20813103
DOI: 10.1016/j.ydbio.2010.08.026
PMCID: PMC2957520

Genes

PDCD2
HCFC1
LIF
NCOR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20813103-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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