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Article

Cdk2ap2 is a novel regulator for self-renewal of murine embryonic stem cells.

Stem cells and development - 1 Nov 2012

Deshpande Amit M, Khalid Omar, Kim Jeffrey J, Kim Yong, Lindgren Anne, Clark Amander T, Wong David T W

Abstract excerpt

In this study we present data to support the role for Cdk2ap2 in regulating self-renewal of mouse embryonic stem cells (mESCs) under permissive conditions, and cell survival during differentiation of the mESCs into terminally differentiated cell types. To understand the function of Cdk2ap2 during early development, we generated mESCs with homozygous disruption of the endogenous Cdk2ap2 locus (Cdk2ap2(tr/tr)). The...

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PMID: 22548356
DOI: 10.1089/scd.2012.0007
PMCID: PMC3475145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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