Article
Association study of interferon-γ, cytosolic phospholipase A2, and cyclooxygenase-2 gene polymorphisms in Alzheimer disease.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Nov 2010
Fehér Agnes, Juhász Anna, Rimanóczy Agnes, Kálmán János, Janka Zoltán
Abstract excerpt
OBJECTIVE: The increased production of proinflammatory mediators such as cytokines and prostaglandins may interact at multiple levels with neurodegeneration in Alzheimer disease (AD). This study was undertaken to evaluate the possible role of interferon-γ (IFN-γ) T+874A, cytoplasmic phospholipase A₂ (cPLA2) BanI, and cyclooxygenase-2 (COX-2) G-765C polymorphisms in AD. METHODS: The study included 237 probable...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
