Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of cyclooxygenase-2 and 5-lipoxygenase polymorphisms in Alzheimer's disease in a population from northern Italy: implication for pharmacogenomics.

Journal of Alzheimer's disease : JAD - 1 Jan 2010

Listì Florinda, Caruso Calogero, Lio Domenico, Colonna-Romano Giuseppina, Chiappelli Martina, Licastro Federico, Candore Giuseppina

Abstract excerpt

Alzheimer's disease (AD) is a neurodegenerative disorder clinically characterized by cognitive deficit with progressive worsening of memory. Recent data indicate that neurons, as well as other brain cells, can express enzymes such as cyclooxygenases (COXs) and 5-lipoxygenase (5-LO) which are considered important in inflammatory cells. Moreover, it has been demonstrated that COX-2 and 5-LO enzymes play a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alzheimer Disease

Share to Arachidonate 5-Lipoxygenase

Share to Cyclooxygenase 2

Share to Gene Frequency

Share to Population Groups

Source

Identifiers

PMID: 20110601
DOI: 10.3233/JAD-2010-1260

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of cyclooxygenase-2 and 5-lipoxygenase polymorphisms in Alzheimer's disease in a population from northern Italy: implication for pharmacogenomics.PMID 20110601Read ↗

The cyclooxygenase 2 -765 C promoter allele is a protective factor for Alzheimer's disease.Semantic proximity Read ↗

Cyclooxygenase-2 gene polymorphisms and risk of Alzheimer's disease: A meta-analysis.Semantic proximity Read ↗

Arachidonate 5-lipoxygenase (ALOX5) gene polymorphism is associated with Alzheimer's disease and body mass index.Semantic proximity Read ↗

5-Lipoxygenase (5-LOX) Promoter Polymorphism in Patients With Early-Onset and Late-Onset Alzheimer's DiseaseSemantic proximity Read ↗

Alzheimer’s Disease and Genetics of Inflammation: A Pharmacogenomic VisionSemantic proximity Read ↗

Association of prostaglandin-endoperoxide synthase 2 (PTGS2) polymorphisms and Alzheimer's disease in Chinese.Semantic proximity Read ↗

Association between polymorphism c.1-765G>C of the COX2 gene and cognitive impairment in individuals 65 years or more with diabetes from a Geriatric Service in Monterrey, Mexico.Semantic proximity Read ↗

Polymorphisms in inflammatory genes and the risk of Alzheimer disease.Semantic proximity Read ↗

The 5-lipoxygenase pathway: oxidative and inflammatory contributions to the Alzheimerâ€™s disease phenotypeSemantic proximity Read ↗

Association study of interferon-γ, cytosolic phospholipase A2, and cyclooxygenase-2 gene polymorphisms in Alzheimer disease.Semantic proximity Read ↗

Angiotensin converting enzyme and endothelial nitric oxide synthase DNA polymorphisms and late onset Alzheimer's disease.Semantic proximity Read ↗

Aromatase and interleukin-10 genetic variants interactively modulate Alzheimer's disease risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.