Article
Crossveinless-2 is required for the relocalization of Chordin protein within the vertebral field in mouse embryos.
Developmental biology - 1 Nov 2010
Zakin Lise, Chang Ellen Y, Plouhinec Jean-Louis, De Robertis E M
Abstract excerpt
Bone morphogenetic proteins (BMPs), as well as the BMP-binding molecules Chordin (Chd), Crossveinless-2 (CV2) and Twisted Gastrulation (Tsg), are essential for axial skeletal development in the mouse embryo. We previously reported a strong genetic interaction between CV2 and Tsg and proposed a role for this interaction in the shaping of the BMP morphogenetic field during vertebral development. In the present...
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