Article
crossveinless defines a new family of Twisted-gastrulation-like modulators of bone morphogenetic protein signalling.
EMBO reports - 1 Mar 2005
Vilmos Peter, Sousa-Neves Rui, Lukacsovich Tamas, Marsh J Lawrence
Abstract excerpt
The Twisted gastrulation (Tsg) proteins are modulators of bone morphogenetic protein (BMP) activity in both vertebrates and insects. We find that the crossveinless (cv) gene of Drosophila encodes a new tsg-like gene. Genetic experiments show that cv, similarly to tsg, interacts with short gastrulation (sog) to modulate BMP signalling. Despite this common property, Cv shows a different BMP ligand specificity as...
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