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Article

Twisted gastrulation mutation suppresses skeletal defect phenotypes in Crossveinless 2 mutant mice.

Mechanisms of development - 1 Jan 2000

Ikeya Makoto, Nosaka Tetsuya, Fukushima Kumi, Kawada Masako, Furuta Yasuhide, Kitamura Toshio, Sasai Yoshiki

Abstract excerpt

Bone morphogenetic protein (BMP) signaling controls various aspects of organogenesis, including skeletal development. We previously demonstrated that the pro-BMP function of Crossveinless 2 (Cv2) is required for axial and non-axial skeletal development in mice. Here, we showed that skeletal defects in the Cv2-null mutant were reversed by the additional deletion of Twisted gastrulation (Tsg). Whereas the Cv2(-/-)...

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Identifiers

PMID: 18644438
DOI: 10.1016/j.mod.2008.06.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Twisted gastrulation mutation suppresses skeletal defect phenotypes in Crossveinless 2 mutant mice.PMID 18644438Read ↗

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