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Article

A functional SUMO-interacting motif in the transactivation domain of c-Myb regulates its myeloid transforming ability.

Oncogene - 13 Jan 2011

Saether T, Pattabiraman D R, Alm-Kristiansen A H, Vogt-Kielland L T, Gonda T J, Gabrielsen O S

Abstract excerpt

c-Myb is an essential hematopoietic transcription factor that controls proliferation and differentiation of progenitors during blood cell development. Whereas sumoylation of the C-terminal regulatory domain (CRD) is known to have a major impact on the activity of c-Myb, no role for noncovalent binding of small ubiquitin-like modifier (SUMO) to c-Myb has been described. Based on the consensus SUMO-interacting...

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Source

Identifiers

PMID: 20802522
DOI: 10.1038/onc.2010.397

Genes

SUMO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A functional SUMO-interacting motif in the transactivation domain of c-Myb regulates its myeloid transforming ability.PMID 20802522Read ↗

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