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Article

Evaluation of the effects of cytochrome P450 nonsynonymous single-nucleotide polymorphisms on tanshinol borneol ester metabolism and inhibition potential.

Drug metabolism and disposition: the biological fate of chemicals - 1 Dec 2010

Liu Duan, Gao Yiwen, Wang Huijuan, Zi Jing, Huang He, Ji Jing, Zhou Ruimin, Nan Yefei, Wang Shixiang, Zheng Xiaohui, Zhu Juanli, Cui Yali, Chen Chao

Abstract excerpt

Nonsynonymous single-nucleotide polymorphisms (nsSNPs) in cytochrome P450 (P450) genes may affect drug metabolism and drug-drug interactions (DDIs), potentially leading to adverse drug reactions. Functional characterization of the nsSNPs in P450 genes is important to help us understand the impact...

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PMID: 20736323
DOI: 10.1124/dmd.110.034439

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20736323-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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