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Article

CYP-nsSNP: a specialized database focused on effect of non-synonymous SNPs on function of CYPs.

Interdisciplinary sciences, computational life sciences - 1 Jun 2012

Zhang Tao, Zhou Qiang, Pang Yushu, Wang Yufang, Jin Chaohui, Huo Juan, Liu Limin Angela, Wei Dongqing

Abstract excerpt

The cytochrome P450 (CYP) enzymes play the central role in synthesis of endogenous substances and metabolism of xenobiotics. The substitution of single amino acid caused by non-synonymous single nucleotide polymorphism (nsSNP) will lead to the change in enzymatic activity of CYP isozymes, especially the drugmetabolizing ability. CYP-nsSNP is a specialized database focused on the effect of nsSNPs on enzymatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22843230
DOI: 10.1007/s12539-012-0125-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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