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The kingdom of the prolyl-isomerase Pin1: The structural and functional convergence and divergence of Pin1

30 Aug 2022

Abstract excerpt

More than 20 years since its discovery, our understanding of Pin1 function in various diseases continues to improve. Pin1 plays a crucial role in pathogenesis and has been implicated in metabolic disorders, cardiovascular diseases, inflammatory diseases, viral infection, cancer and neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's disease. In particular, the role of Pin1 in...

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PMID: 36111342
DOI: 10.3389/fcell.2022.956071

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