Article
Dissection of corticotropin-releasing factor system involvement in locomotor sensitivity to methamphetamine.
Genes, brain, and behavior - 1 Feb 2011
Giardino W J, Pastor R, Anacker A M J, Spangler E, Cote D M, Li J, Stenzel-Poore M P, Phillips T J, Ryabinin A E
Abstract excerpt
Sensitivity to the euphoric and locomotor-activating effects of drugs of abuse may contribute to risk for excessive use and addiction. Repeated administration of psychostimulants such as methamphetamine (MA) can result in neuroadaptive consequences that manifest behaviorally as a progressive escalation of locomotor activation, termed psychomotor sensitization. The present studies addressed the involvement of...
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