Article
Effects of access condition on substance use disorder-like phenotypes in male and female rats self-administering MDPV or cocaine.
Drug and alcohol dependence - 1 Oct 2024
Doyle Michelle R, Beltran Nina M, Bushnell Mark S A, Syed Maaz, Acosta Valeria, Desai Marisa, Rice Kenner C, Serafine Katherine M, Gould Georgianna G, Daws Lynette C, Collins Gregory T
Abstract excerpt
Substance use disorder (SUD) is a heterogeneous disorder, where severity, symptoms, and patterns of use vary across individuals. Yet, when rats self-administer cocaine under short-access conditions, their behavior tends to be well-regulated, though individual differences can emerge with long- or intermittent-access. In contrast, significant individual differences emerge when rats self-administer...
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