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Article

Role of cannabinoid type 1 receptors in locomotor activity and striatal signaling in response to psychostimulants.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Jun 2007

Corbillé Anne-Gaëlle, Valjent Emmanuel, Marsicano Giovanni, Ledent Catherine, Lutz Beat, Hervé Denis, Girault Jean-Antoine

Abstract excerpt

A single administration of cocaine or D-amphetamine produces acute hyperlocomotion and long-lasting increased sensitivity to subsequent injections. This locomotor sensitization reveals the powerful ability of psychostimulants to induce brain plasticity and may participate in the alterations that underlie addiction. We investigated the role of cannabinoid receptor type 1 (CB1-R) in the effects of a single...

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Source

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Identifiers

PMID: 17596442
DOI: 10.1523/JNEUROSCI.3936-06.2007
PMCID: PMC6672215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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