Article
A mutation within the β subunit of Escherichia coli RNA polymerase impairs transcription from bacteriophage T4 middle promoters.
Journal of bacteriology - 1 Nov 2010
James Tamara D, Cashel Michael, Hinton Deborah M
Abstract excerpt
During infection of Escherichia coli, bacteriophage T4 usurps the host transcriptional machinery, redirecting it to the expression of early, middle, and late phage genes. Middle genes, whose expression begins about 1 min postinfection, are transcribed both from the extension of early RNA into middle genes and by the activation of T4 middle promoters. Middle-promoter activation requires the T4 transcriptional...
Topics
- Amino Acid Sequence
- Bacteriophage T4
- DNA-Directed RNA Polymerases
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Viral
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Protein Subunits
- RNA, Bacterial