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Article

The asiA gene product of bacteriophage T4 is required for middle mode RNA synthesis.

Journal of bacteriology - 1 Jul 1994

Ouhammouch M, Orsini G, Brody E N

Abstract excerpt

The asiA gene of bacteriophage T4 encodes a 10-kDa peptide which binds strongly in vitro to the sigma 70 subunit of Escherichia coli RNA polymerase, thereby weakening sigma 70-core interactions and inhibiting sigma 70-dependent transcription. To assess the physiological role of this protein, we have introduced an amber mutation into the proximal portion of the asiA gene. On suppressor-deficient hosts, this mutant...

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Identifiers

PMID: 8021178
DOI: 10.1128/jb.176.13.3956-3965.1994
PMCID: PMC205593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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