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Article

Mutational analysis of sigma70 region 4 needed for appropriation by the bacteriophage T4 transcription factors AsiA and MotA.

Journal of molecular biology - 10 Nov 2006

Baxter Kimberly, Lee Jennifer, Minakhin Leonid, Severinov Konstantin, Hinton Deborah M

Abstract excerpt

Transcriptional activation of bacteriophage T4 middle promoters requires sigma70-containing Escherichia coli RNA polymerase, the T4 activator MotA, and the T4 co-activator AsiA. T4 middle promoters contain the sigma70 -10 DNA element. However, these promoters lack the sigma70 -35 element, having instead a MotA box centered at -30, which is bound by MotA. Previous work has indicated that AsiA and MotA interact...

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Identifiers

PMID: 16996538
DOI: 10.1016/j.jmb.2006.08.074
PMCID: PMC1698951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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