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Article

Binding of the bacteriophage T4 transcriptional activator, MotA, to T4 middle promoter DNA: evidence for both major and minor groove contacts.

Journal of molecular biology - 30 Jul 1999

Sharma M, Marshall P, Hinton D M

Abstract excerpt

During infection, the bacteriophage T4 transcriptional activator MotA, the co-activator AsiA, and host RNA polymerase are needed to transcribe from T4 middle promoters. Middle promoters contain a -10 region recognized by the sigma(70)subunit of RNA polymerase and a MotA box centered at -30 that is bound by MotA. We have investigated how the loss or modification of base determinants within the MotA box sequence...

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Source

Identifiers

PMID: 10438591
DOI: 10.1006/jmbi.1999.2928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Binding of the bacteriophage T4 transcriptional activator, MotA, to T4 middle promoter DNA: evidence for both major and minor groove contacts.PMID 10438591Read ↗

Mutational analysis of sigma70 region 4 needed for appropriation by the bacteriophage T4 transcription factors AsiA and MotA.Semantic proximity Read ↗

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A mutation within the β subunit of Escherichia coli RNA polymerase impairs transcription from bacteriophage T4 middle promoters.Semantic proximity Read ↗

Substitutions in bacteriophage T4 AsiA and Escherichia coli sigma(70) that suppress T4 motA activation mutations.Semantic proximity Read ↗

The asiA gene product of bacteriophage T4 is required for middle mode RNA synthesis.Semantic proximity Read ↗

The activation domain of the MotA transcription factor from bacteriophage T4.Semantic proximity Read ↗

The role of an upstream promoter interaction in initiation of bacterial transcription.Semantic proximity Read ↗

Determinants of affinity and activity of the anti-sigma factor AsiA.Semantic proximity Read ↗

The bacteriophage T4 late-transcription coactivator gp33 binds the flap domain of Escherichia coli RNA polymerase.Semantic proximity Read ↗

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The intercalating beta-hairpin of T7 RNA polymerase plays a role in promoter DNA melting and in stabilizing the melted DNA for efficient RNA synthesis.Semantic proximity Read ↗

Insights into the quality of DnaA boxes and their cooperativity.Semantic proximity Read ↗

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