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Article

An E. coli B mutation, rpoB5081, that prevents growth of phage T4 strains defective in host DNA degradation.

FEMS microbiology letters - 1 Dec 1997

Miller E S, Shih G C, Chang S K, Ballard D N

Abstract excerpt

An E. coli B Tab strain, EM121, was isolated that restricts T4 denA (DNA endonuclease II) mutants at 37 degrees C and above, but is permissive for wild-type T4 at all temperatures examined. At 42 degrees C, other mutants affected in nucleic acid metabolism (T4 dexA, regA and uvsW strains) are also restricted. Genetic analysis revealed that one mutation (rpoB5081) in the RNA polymerase beta subunit gene is...

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PMID: 9418245
DOI: 10.1111/j.1574-6968.1997.tb12760.x

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