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Article

Rs1347093 polymorphism contributes to radiation pneumonitis in lung cancer patients through regulating miR-216a-5p expression.

Functional & integrative genomics - 10 Jul 2026

Luo Wu, Liu Cuifang, Dai Yuejie, Hong Yin, Zhang Haibo

Abstract excerpt

The pathogenesis of radiation pneumonitis (RP) is complex, involving multiple genetic and molecular factors. Single-nucleotide polymorphisms (SNPs) at specific microRNA gene loci can influence miRNA expression, even affect disease progression. Genotype distribution of rs1347093 in RP and non-RP groups was analyzed, and the underlying mechanism was explored in human pulmonary microvascular endothelial cells...

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PMID: 42430022
DOI: 10.1007/s10142-026-01954-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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