Article
P53 codon 72 Arg/Pro polymorphism and lung cancer risk in Asians: an updated meta-analysis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2013
Wang Siyang, Lan Xingang, Tan Sheng, Wang Siwen, Li Yu
Abstract excerpt
The polymorphism of p53 codon 72, a transversion of G to C (Arg to Pro), has been demonstrated to be associated with the risk for lung cancer. However, individual studies conducted in Asians have provided conflicting and inconclusive findings. Thus, we performed a meta-analysis by pooling all currently available case-control studies to estimate the effect of p53 codon 72 Arg/Pro polymorphism on the development of...
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