Article
s-RT-MELT: a novel technology for mutation screening.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Li Jin, Makrigiorgos G Mike
Abstract excerpt
The fast growing understanding of genetic pathways that mediate cancer etiology, biology, and personalized medicine leads to an increasing need for extensive and reliable mutation screening on a population or on a single patient basis. Here we describe s-RT-MELT, a novel technology that enables expanded-throughput enzymatic mutation scanning in clinical cancer samples for germline or low-level somatic mutations,...
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