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Article

Expression of micro-RNA-145 is regulated by a highly conserved genomic sequence 3' to the pre-miR.

Journal of cellular physiology - 1 Mar 2011

La Rocca Gaspare, Shi Bin, Sepp-Lorenzino Laura, Baserga Renato

Abstract excerpt

Micro-RNA-145 (miR145), a tumor suppressor miR, dramatically inhibits growth of cancer cells in culture and plays a significant role in human stem cells differentiation. We have isolated a human genomic sequence of 864 bp comprising the pre-miR and its flanking sequences. The cloned miR145 genomic sequence expresses a mature miR145 in transfected cells. We show here that flanking sequences on either side of the...

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Identifiers

PMID: 20717966
DOI: 10.1002/jcp.22368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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