Article
Fine mapping of epistatic genetic determinants of blood pressure on rat chromosome 5.
Journal of hypertension - 1 Jul 2018
Waghulde Harshal, Pillai Resmi, Cheng Xi, Nie Ying, Mell Blair, Joe Bina
Abstract excerpt
BACKGROUND: Previously, using linkage analysis and substitution mapping, two closely-linked interactive blood pressure quantitative trait loci (QTLs), BP QTL1 and BP QTL2, were located within a 13.96 Mb region from 117894038 to 131853815 bp (RGSC 3.4 version) on rat chromosome 5 (RNO5). This was done by using a series of congenic strains consisting of genomic segments of the Dahl salt-sensitive (S) rat...
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