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Article

Phenotypic stability and metastatic behaviour of serially xenografted rat mesotheliomas.

British journal of cancer - 1 Aug 1990

Edwards R E, Hill R J, Brown D G, Carthew P

Abstract excerpt

Mesotheliomas induced in rats by intrapleural injection of the fibrous zeolite, erionite, were serially transplanted in nude mice for up to ten generations. The cell phenotypes (epithelial or sarcomatous) were well maintained during passaging, as determined morphologically and by the expression of the cytokeratin markers demonstrated in normal mesothelial cells. Some of the tumours occasionally produced...

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Identifiers

PMID: 2167119
DOI: 10.1038/bjc.1990.260
PMCID: PMC1971811

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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