Phenotypic stability and metastatic behaviour of serially xenografted rat mesotheliomas.

doi:10.1038/bjc.1990.260

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Article

Phenotypic stability and metastatic behaviour of serially xenografted rat mesotheliomas.

British journal of cancer - 1 Aug 1990

Edwards R E, Hill R J, Brown D G, Carthew P

Abstract excerpt

Mesotheliomas induced in rats by intrapleural injection of the fibrous zeolite, erionite, were serially transplanted in nude mice for up to ten generations. The cell phenotypes (epithelial or sarcomatous) were well maintained during passaging, as determined morphologically and by the expression o...

Topics

Aluminum Silicates
Animals
Female
Male
Mesothelioma
Mice
Neoplasm Metastasis
Neoplasm Transplantation
Phenotype
Rats
Transplantation, Heterologous
Tumor Cells, Cultured
Zeolites

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