Article
Loss of basal cell phenotype with acquisition of lung-colonizing capability in mouse mammary tumors.
Breast cancer research and treatment - 1 Jan 2000
Tsubura A, Inui T, Morii S, Dairkee S H, Oikawa T, Matsuzawa A
Abstract excerpt
A transplantable pregnancy-dependent mouse mammary tumor, TPDMT-4, and its ovarian-dependent (T4-OR26) and autonomous (T4-OI96, T4-OI145, T4-OI165, T4-OI320 and T4-OI320CY) sublines were examined immunohistochemically for the expression of keratin 14 and type IV collagen. T4-OI96, T4-OI145, and T4-OI165, but not T4-OR26, T4-OI320, or T4-OI320CY, formed lung colonies (metastasis) after intravenous injection as a...
Topics
- Animals
- Collagen
- Immunoenzyme Techniques
- Keratins
- Lung Neoplasms
- Mammary Neoplasms, Experimental
- Mice
- Phenotype
- Tumor Cells, Cultured