Article
Changes of phenotypic characteristics of variants derived from Lewis lung carcinoma during long-term in vitro growth.
Clinical & experimental metastasis - 1 Jan 2000
Sacchi A, Mauro F, Zupi G
Abstract excerpt
Two cultured cell clones derived from Lewis lung carcinoma (3LL), which have been shown to differ in their metastatic potential, were studied for their phenotypic stability in vitro. Several growth properties (lag-phase duration, doubling time, saturation density, cell shedding, plating efficiency) have been monitored for more than three years. The ability to induce primary tumors and metastasis, together with...
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