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Article

A genetic mosaic screen of essential zygotic genes in Caenorhabditis elegans.

Genetics - 1 Jun 1991

Bucher E A, Greenwald I

Abstract excerpt

We have devised a simple genetic mosaic screen, which circumvents the difficulties posed by phenotypic analysis of early lethal mutants, to analyze essential zygotic genes in Caenorhabditis elegans. The screen attempts to distinguish genes involved in cell type and/or lineage specific processes such as determination, differentiation or morphogenesis from genes involved in general processes such as intermediary...

Topics

Alleles
Animals
Caenorhabditis
Cell Division
Genes, Lethal
Genetic Complementation Test
Genetic Techniques
Mosaicism
Multigene Family
Mutagenesis
Phenotype
Zygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2071016
DOI: 10.1093/genetics/128.2.281
PMCID: PMC1204466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2071016-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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