Article
Investigating C. elegans development through mosaic analysis.
Development (Cambridge, England) - 1 Oct 2003
Yochem John, Herman Robert K
Abstract excerpt
The analysis of genetically mosaic worms, in which some cells carry a wild-type gene and others are homozygous mutant, can reveal where in the animal a gene acts to prevent the appearance of a mutant phenotype. In this primer article, we describe how Caenorhabditis elegans genetic mosaics are generated, identified and analyzed, and we discuss examples in which the analysis of mosaic worms has provided important...
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