Article
Implication of IL-33 gene polymorphism in Chinese patients with Alzheimer's disease.
Neurobiology of aging - 1 May 2012
Yu Jin-Tai, Song Jing-Hui, Wang Nai-Dong, Wu Zhong-Chen, Zhang Qun, Zhang Na, Zhang Wei, Xuan Shi-Ying, Tan Lan
Abstract excerpt
Interleukin-33 (IL-33), a newly described member of the IL-1 family, is located on chromosome 9p24, a chromosomal region of interest in Alzheimer's disease (AD) defined by many genome-wide studies. Three intronic rs1157505, rs11792633, and rs7044343 single nucleotide polymorphisms (SNPs) within IL-33 have recently been reported to be associated with risk of AD in Caucasian populations. In order to assess the...
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