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Article

Association between genetic polymorphisms in the XRCC1, XRCC3, XPD, GSTM1, GSTT1, MSH2, MLH1, MSH3, and MGMT genes and radiosensitivity in breast cancer patients.

International journal of radiation oncology, biology, physics - 1 Sept 2011

Mangoni Monica, Bisanzi Simonetta, Carozzi Francesca, Sani Cristina, Biti Giampaolo, Livi Lorenzo, Barletta Emanuela, Costantini Adele Seniori, Gorini Giuseppe

Abstract excerpt

PURPOSE: Clinical radiosensitivity varies considerably among patients, and radiation-induced side effects developing in normal tissue can be therapy limiting. Some single nucleotide polymorphisms (SNPs) have been shown to correlate with hypersensitivity to radiotherapy. We conducted a prospective study of 87 female patients with breast cancer who received radiotherapy after breast surgery. We evaluated the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20708344
DOI: 10.1016/j.ijrobp.2010.04.023

Genes

MSH2
MSH3
XRCC1
XRCC3
GSTM1
GSTT1
MGMT
MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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