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Genetic risk score and acute skin toxicity after breast radiation therapy.

Cancer biotherapy & radiopharmaceuticals - 1 Sept 2014

Borghini Andrea, Vecoli Cecilia, Mercuri Antonella, Petruzzelli Maria Fonte, D'Errico Maria Patrizia, Portaluri Maurizio, Andreassi Maria Grazia

Abstract excerpt

Genetic predisposition has been shown to affect the severity of skin complications in breast cancer patients after radiotherapy. Limited data exist regarding the use of a genetic risk score (GRS) for predicting risk of tissue radiosensitivity. We evaluated the impact of different single-nucleotide polymorphisms (SNPs) in genes related to DNA repair mechanisms and oxidative stress response combined in a GRS on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25099761
DOI: 10.1089/cbr.2014.1620

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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