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Article

Common variants of eNOS and XRCC1 genes may predict acute skin toxicity in breast cancer patients receiving radiotherapy after breast conserving surgery.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 May 2012

Terrazzino Salvatore, La Mattina Pierdaniele, Masini Laura, Caltavuturo Tina, Gambaro Giuseppina, Canonico Pier Luigi, Genazzani Armando A, Krengli Marco

Abstract excerpt

PURPOSE: To evaluate the impact of functional polymorphisms in genes related to DNA repair mechanisms (XRCC1, TP53, MSH2, MSH3, XPD), oxidative stress response (GSTP1, GSTA1, eNOS, SOD2) and fibroblast proliferation (TGFβ1) on the risk of acute skin toxicity in breast cancer patients receiving ra...

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Source

Identifiers

PMID: 22248507
DOI: 10.1016/j.radonc.2011.12.002

Genes

XRCC1
GSTA1
GSTP1
MSH2
MSH3
SOD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22248507-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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