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Article

Fine mapping and expression of candidate genes within the chromosome 10 QTL region of the high and low alcohol-drinking rats.

Alcohol (Fayetteville, N.Y.) - 1 Sept 2010

Bice Paula J, Liang Tiebing, Zhang Lili, Graves Tamara J, Carr Lucinda G, Lai Dongbing, Kimpel Mark W, Foroud Tatiana

Abstract excerpt

The high and low alcohol-drinking (HAD and LAD) rats were selectively bred for differences in alcohol intake. The HAD/LAD rats originated from the N/Nih heterogeneous stock developed from intercrossing eight inbred rat strains. The HAD×LAD F2 were genotyped, and a powerful analytical approach, using ancestral recombination and F2 recombination, was used to narrow a quantitative trait loci (QTL) for alcohol...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20705418
DOI: 10.1016/j.alcohol.2010.06.004
PMCID: PMC5514542

Genes

LAD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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