Article
Analyses of quantitative trait loci contributing to alcohol preference in HAD1/LAD1 and HAD2/LAD2 rats.
Alcoholism, clinical and experimental research - 1 Nov 2003
Carr Lucinda G, Habegger Kirk, Spence John, Ritchotte Aimee, Liu Lixiang, Lumeng Lawrence, Li Ting-Kai, Foroud Tatiana
Abstract excerpt
BACKGROUND: The high-alcohol-drinking (HAD1/HAD2) and low-alcohol-drinking (LAD1/LAD2) rat lines, derived from the N/NIH rat, were developed by using a within-family selection and rotational breeding design for alcohol preference and alcohol consumption. Previously, a 20-cM genome screen identified quantitative trait loci (QTLs) on chromosomes 5, 10, 12, and 16 by using F2 progeny from HAD1 and LAD1 animals....
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