Article
Identification of QTLs influencing alcohol preference in the High Alcohol Preferring (HAP) and Low Alcohol Preferring (LAP) mouse lines.
Behavior genetics - 1 Mar 2006
Bice Paula J, Foroud Tatiana, Carr Lucinda G, Zhang Lili, Liu Lixiang, Grahame Nicholas J, Lumeng Lawrence, Li Ting-Kai, Belknap John K
Abstract excerpt
The High- and Low-Alcohol Preferring (HAP1/LAP1 and HAP2/LAP2) mouse lines were developed by selective breeding for differences in alcohol preference. They represent the only extant selectively bred mouse lines developed for this alcohol phenotype. Therefore, they provide a unique resource for QTL detection and mapping. Importantly, neither of the replicate lines is inbred and therefore, novel study designs can...
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