Article
Genomewide SNP screen to detect quantitative trait loci for alcohol preference in the high alcohol preferring and low alcohol preferring mice.
Alcoholism, clinical and experimental research - 1 Mar 2009
Bice Paula, Valdar William, Zhang Lili, Liu Lixiang, Lai Dongbing, Grahame Nicholas, Flint Jonathan, Li Ting-Kai, Lumeng Lawrence, Foroud Tatiana
Abstract excerpt
BACKGROUND: The high and low alcohol preferring (HAP1 and LAP1) mouse lines were selectively bred for differences in alcohol intake. The HAP1 and LAP1 mice are essentially noninbred lines that originated from the outbred colony of HS/Ibg mice, a heterogeneous stock developed from intercrossing 8 inbred strains of mice. METHODS: A total of 867 informative SNPs were genotyped in 989 HAP1 x LAP1 F2, 68 F1s, 14...
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