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Article

Genome-wide association study of alcohol dependence implicates a region on chromosome 11.

Alcoholism, clinical and experimental research - 1 May 2010

Edenberg Howard J, Koller Daniel L, Xuei Xiaoling, Wetherill Leah, McClintick Jeanette N, Almasy Laura, Bierut Laura J, Bucholz Kathleen K, Goate Alison, Aliev Fazil, Dick Danielle, Hesselbrock Victor, Hinrichs Anthony, Kramer John, Kuperman Sam, Nurnberger John I, Rice John P, Schuckit Marc A, Taylor Robert, Todd Webb B, Tischfield Jay A, Porjesz Bernice, Foroud Tatiana

Abstract excerpt

BACKGROUND: Alcohol dependence is a complex disease, and although linkage and candidate gene studies have identified several genes associated with the risk for alcoholism, these explain only a portion of the risk. METHODS: We carried out a genome-wide association study (GWAS) on a case-control sample drawn from the families in the Collaborative Study on the Genetics of Alcoholism. The cases all met diagnostic...

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Identifiers

PMID: 20201924
DOI: 10.1111/j.1530-0277.2010.01156.x
PMCID: PMC2884073

Genes

ADCY3
CPE
GATA4
OSBPL5
PHLDA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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