Article
Mouse chromosome 17 candidate modifier genes for thrombosis.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2010
Sa Qila, Hart Erika, Nadeau Joseph H, Hoover-Plow Jane L
Abstract excerpt
Two overlapping quantitative trait loci (QTLs) for clot stability, Hmtb8 and Hmtb9, were identified on mouse chromosome 17 in an F2 intercross derived from C57BL/6J (B6) and B6-Chr17(A/J) (B6-Chr17) mouse strains. The intervals were in synteny with a QTL for thrombotic susceptibility on chromosome 18 in a human study, and there were 23 homologs between mouse and human. The objective of this study was to determine...
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