Article
Quantitative trait locus analysis for hemostasis and thrombosis.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 2008
Sa Qila, Hart Erika, Hill Annie E, Nadeau Joseph H, Hoover-Plow Jane L
Abstract excerpt
Susceptibility to thrombosis varies in human populations as well as many in inbred mouse strains. The objective of this study was to characterize the genetic control of thrombotic risk on three chromosomes. Previously, utilizing a tail-bleeding/rebleeding assay as a surrogate of hemostasis and thrombosis function, three mouse chromosome substitution strains (CSS) (B6-Chr5(A/J), Chr11(A/J), Chr17(A/J)) were...
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