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Article

Germline mutation analysis of hPMS2 gene in Chinese families with hereditary nonpolyposis colorectal cancer.

World journal of gastroenterology - 14 Aug 2010

Sheng Xia, Zhou Heng-Hua, Zhou Xiao-Yan, Du Xiang, Zhang Tai-Ming, Cai San-Jun, Sheng Wei-Qi, Shi Da-Ren

Abstract excerpt

AIM: To study the germline mutation of hPMS2 gene in 26 unrelated Chinese hereditary nonpolyposis colorectal cancer (HNPCC) probands and to fulfill the screening strategy for HNPCC in Chinese. METHODS: Genomic DNA was extracted from the peripheral blood. To avoid the interference of pseudogene in detection of the remaining 11 exons (exon 1-5, 9, 11-15), long-range polymerase chain reaction (PCR) was conducted to...

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Share to Adenosine Triphosphatases
Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair Enzymes

Share to Germ-Line Mutation

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Share to Mismatch Repair Endonuclease PMS2

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Source

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Identifiers

PMID: 20698049
DOI: 10.3748/wjg.v16.i30.3847
PMCID: PMC2921098

Genes

PMS2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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