Article
Genetic diagnosis strategy of hereditary non-polyposis colorectal cancer.
World journal of gastroenterology - 28 Feb 2009
Sheng Jian-Qiu, Zhang Hong, Ji Min, Fu Lei, Mu Hong, Zhang Ming-Zhi, Huang Ji-Sheng, Han Min, Li Ai-Qin, Wei Zhi, Sun Zi-Qin, Wu Zi-Tao, Xia Chang-Hong, Li Shi-Rong
Abstract excerpt
AIM: To study the characteristics of mismatch repair gene mutation of Chinese hereditary non-polyposis colorectal cancer (HNPCC) and hMLH1 gene promoter methylation, and to improve the screening strategy and explore the pertinent test methods. METHODS: A systematic analysis of 30 probands from HNPCC families in the north of China was performed by immunohistochemistry, microsatellite instability (MSI), gene...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
